Medical support in surgery for pheochromocytoma

The occurrence of hypertensive crises, arrhythmias and hypotensive crises during surgery for pheochromocytoma can be prevented both preoperatively and intraoperatively by adequate alpha-adrenergic blockade and volume replacement. Only in a few cases is additional beta-adrenergic blockade necessary....

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Bibliographic Details
Published inHelvetica chirurgica acta Vol. 46; no. 3; p. 287
Main Author Schmucki, O
Format Journal Article
LanguageGerman
Published Switzerland 01.08.1979
Subjects
Adrenal Gland Neoplasms - surgery
Arrhythmias, Cardiac - etiology
Arrhythmias, Cardiac - prevention & control
Humans
Hypertension - etiology
Hypertension - prevention & control
Hypotension - etiology
Hypotension - prevention & control
Intraoperative Complications - prevention & control
Lidocaine - therapeutic use
Phenoxybenzamine - therapeutic use
Phentolamine - therapeutic use
Pheochromocytoma - surgery
Premedication
Propranolol - therapeutic use
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Summary:The occurrence of hypertensive crises, arrhythmias and hypotensive crises during surgery for pheochromocytoma can be prevented both preoperatively and intraoperatively by adequate alpha-adrenergic blockade and volume replacement. Only in a few cases is additional beta-adrenergic blockade necessary. Preoperatively the author uses phenoxybenzamine (Dibenicyline) as alpha-blockade in a dose of 20-30 mg daily, and propanolol (Inderal) as beta-blockade in a dose of 4 X 20 mg daily, both given orally. Intraoperatively he gives preference to alpha-adrenergic receptor blockers with a short halflife, i.e. phentolamine (Regitin) and lidocaine or pranolol as the beta-adrenergic blocker.
ISSN:0018-0181