Comparative study of the immunoglobulin content in persons from leptospirosis foci in different geographical zones of the RSFSR

The authors carried out a comparative study of the content of serum immunoglobulins in persons from the leptospirosis foci of various geographical zones of the RSFSR: European part--the Centre (Moscow and Ryazan regions), the South (Checheno-Ingush ASSR and Krasnodar Territory), and Western Siberia...

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Published inŽurnal mikrobiologii, ėpidemiologii i immunobiologii no. 5; p. 122
Main Authors Baryshev, P M, Shishkina, Z S, Chernukha, Iu G, Kokovin, I L, Malkina, L A
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.05.1978
Subjects
Adolescent
Adult
Child
Child, Preschool
Disease Reservoirs
Humans
Immunoglobulin A - analysis
Immunoglobulin G - analysis
Immunoglobulin M - analysis
Infant
Infant, Newborn
Leptospirosis - immunology
Middle Aged
Russia
Weil Disease - immunology
Russia
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Summary:The authors carried out a comparative study of the content of serum immunoglobulins in persons from the leptospirosis foci of various geographical zones of the RSFSR: European part--the Centre (Moscow and Ryazan regions), the South (Checheno-Ingush ASSR and Krasnodar Territory), and Western Siberia (Altai territory), Leptospira of serological group Pomona, Grippotyphosa, and Hbedomadis served as the causative agents of the diseases. It appeared that the annual course of the climatic factors acted equally (inhibitory action) on the immuno-globulin metabolism in the residents of temperate and southern zones of the RSFSR at the warm period of the year (May-September), and in the Western Siberia- in winter. However, irrespective of the time of the year, the level of immunoglobulins G and A was greater in the residents of Western Siberia than in the native population of the European part. There proved to be no correlation between the levels of leptospirosis seropositivity in the foci of infection under study and the serum immunoglobulins in local residents of various geographical zones.
ISSN:0372-9311