Myocardial perfusion in myocardiopathies: study at rest and during induced tachycardia

The authors have compared myocardial perfusion, i.e. the coronary blood flow per unit of myocardial mass, in 9 patients with cardiomyopathy and 5 normal subjects, both at rest and during coronary sinus pacing-induced tachycardia at a rate of 150 beats/mn. In the cardiomyopathies, myocardial perfusio...

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Bibliographic Details
Published inArchives des maladies du coeur et des vaisseaux Vol. 71; no. 8; p. 878
Main Authors Pasternac, A, Noble, J, Streulens, Y, Lespérance, J, Bourassa, M G
Format Journal Article
LanguageFrench
Published France 01.08.1978
Subjects
Cardiac Pacing, Artificial
Cardiomyopathies - diagnosis
Cardiomyopathies - physiopathology
Coronary Circulation
Heart Failure - physiopathology
Heart Rate
Humans
Ischemia
Lactates - metabolism
Myocardium - metabolism
Oxygen Consumption
Rest
Tachycardia - physiopathology
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Summary:The authors have compared myocardial perfusion, i.e. the coronary blood flow per unit of myocardial mass, in 9 patients with cardiomyopathy and 5 normal subjects, both at rest and during coronary sinus pacing-induced tachycardia at a rate of 150 beats/mn. In the cardiomyopathies, myocardial perfusion was found to be decreased at rest, and to remain abnormally low during induced tachycardia despite the evidence for a significant coronary reserve. During pacing there were, in addition to induced chest pain, indirect signs of sub-endocardial ischaemia which could explain the angina of effort found in certain cardiomyopathies, especially those of the obstructive hypertrophic type.
ISSN:0003-9683