Evaluation of the role of specific antimeningococcal antibodies in the spread of meningococcal carrier states in collectives

The results of serological, bacteriological and epidemiological studies carried out in populations with different epidemic pattern of meningococcal infection are presented. A-group specific antibody was found to have the leading role in the intensity of the spread of meningococcal infection in the p...

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Published inŽurnal mikrobiologii, ėpidemiologii i immunobiologii no. 9; p. 18
Main Authors Demina, A A, Pokrovskiĭ, V I, Kuz'menko, S V, Deviatkina, N P, Semina, N A
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.09.1979
Subjects
Antibodies, Bacterial
Carrier State - microbiology
Carrier State - transmission
Humans
Meningococcal Infections - microbiology
Meningococcal Infections - transmission
Nasopharynx - microbiology
Neisseria meningitidis - immunology
Serotyping
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Summary:The results of serological, bacteriological and epidemiological studies carried out in populations with different epidemic pattern of meningococcal infection are presented. A-group specific antibody was found to have the leading role in the intensity of the spread of meningococcal infection in the populations. The presence of antibody to this antigen in 16.7% of serum samples inhibited dissemination of meningococci in the populations. Simultaneously with an increase in the herd immunity level to 34.8% the attenuation of the active meningococcal dissemination cycle was observed. Meningococci isolated in the populations with different epidemic patterns of meningococcal infection were shown to have different ecological properties.
ISSN:0372-9311