Effect of dilysosomal macrophages on the development and outcome of pneumonia induced by the causative agent of enzootic abortion of sheep

Repeated intranasal injections of increasing doses of bacterial lipopolysaccharide pyrogenal resulted in accumulation of numerous macrophages in the upper and middle parts of the mouse lungs; these macrophages were filled with leukocyte lysosomes. In these animals dilysosomal macrophages increased l...

Full description

Saved in:
Bibliographic Details
Published inBiulleten' eksperimental'noi biologii i meditsiny Vol. 81; no. 4; p. 440
Main Authors Pigarevskiĭ, V E, Tolybekov, A S
Format Journal Article
LanguageRussian
Published Russia (Federation) 1976
Subjects
Abortion, Veterinary - microbiology
Animals
Chlamydia Infections - prevention & control
Female
Lysosomes - immunology
Macrophages - immunology
Male
Mice
Pneumonia - prevention & control
Pregnancy
Pyrogens - therapeutic use
Sheep
Sheep Diseases - microbiology
Online AccessGet more information

Cover

More Information
Summary:Repeated intranasal injections of increasing doses of bacterial lipopolysaccharide pyrogenal resulted in accumulation of numerous macrophages in the upper and middle parts of the mouse lungs; these macrophages were filled with leukocyte lysosomes. In these animals dilysosomal macrophages increased local resistance to the agent of enzootic ewe abortion and thus could change the lethal form of induced pneumonia into the nonlethal one.
ISSN:0365-9615