Formation of increased delayed hypersensitivity to the microbial antigen in animals preliminarily sensitized with pollen

Combined forms of allergy to the wormwood pollen and brucellae was experimentally reproduced. Guinea pigs were sensitized primarily with the wormwood pollen, and in 3 weeks, 2 and 4 weeks with brucellae, in addition. Preliminary (2 and 4 weeks before brucellae administration) sensitization with the...

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Bibliographic Details
Published inŽurnal mikrobiologii, ėpidemiologii i immunobiologii no. 1; p. 110
Main Authors Ermekova, R K, Sukhodoeva, G S
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.01.1978
Subjects
Allergens - administration & dosage
Animals
Antigens, Bacterial - administration & dosage
Brucella abortus - immunology
Female
Guinea Pigs
Hypersensitivity, Delayed
Male
Pollen
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Summary:Combined forms of allergy to the wormwood pollen and brucellae was experimentally reproduced. Guinea pigs were sensitized primarily with the wormwood pollen, and in 3 weeks, 2 and 4 weeks with brucellae, in addition. Preliminary (2 and 4 weeks before brucellae administration) sensitization with the said pollen aided accelerated and marked formation of delayed allergy to the microbial antigen. The effect of intensification of microbial allergy was temporary. In administration of the microbes directly after the pollen allergen no significant influence of the latter on the formation of allergic reactivity to brucellae was noted.
ISSN:0372-9311