Experimental evaluation of mechanical haemolysis with Starr-Edwards, Kay-Shiley and Björk-Shiley valves

Mechanical cell damage was studied in vitro with three types of prostheses: Starr-Edwards, Kay-Shiley and Björk-Shiley valves. Mechanical cell damage was found to be closely related to the flow characteristics in the prosthesis. Considering valves of similar orifice diameter, Björk-Shiley valves pro...

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Bibliographic Details
Published inScandinavian journal of thoracic and cardiovascular surgery Vol. 10; no. 2; p. 117
Main Authors Sallam, I A, Shaw, A, Bain, W H
Format Journal Article
LanguageEnglish
Published Sweden 1976
Subjects
Blood Flow Velocity
Blood Pressure
Evaluation Studies as Topic
Heart Valve Prosthesis - adverse effects
Hemolysis
Models, Biological
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Summary:Mechanical cell damage was studied in vitro with three types of prostheses: Starr-Edwards, Kay-Shiley and Björk-Shiley valves. Mechanical cell damage was found to be closely related to the flow characteristics in the prosthesis. Considering valves of similar orifice diameter, Björk-Shiley valves produced the lowest rate of haemolysis. This is due to the improved haemodynamic characteristics of the valve which resulted from the laminar type of flow. With Starr-Edwards valves, smaller sizes produced unacceptably high rates of haemolysis. Increasing the mean forward flow across the valve resulted in a disproportionate rise in the energy loss and the rate of haemolysis when compared with Björk-Shiley valves of similar annulus diameters.
ISSN:0036-5580