Effect of haemolysin of Pseudomonas aeruginosa on Ehrlich ascites tumor cells

Haemolysin of Pseudomonas aeruginosa exerts toxic effects upon the metabolism of Ehrlich ascitic tumor cells : morphological changes appear readily ; respiration is inhibited more slowly ; the lethal effect determined by intraperitoneal injection of tumor cells is neutralized. Inhibition with human...

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Bibliographic Details
Published inComptes rendus des seances de la Societe de biologie et de ses filiales Vol. 172; no. 5; p. 879
Main Authors Borderon, E, Narcisse, G, Vargues, R
Format Journal Article
LanguageFrench
Published France 1978
Subjects
Animals
Blood
Carcinoma, Ehrlich Tumor - pathology
Carcinoma, Ehrlich Tumor - physiopathology
Cell Survival - drug effects
Hemolysin Proteins - pharmacology
Humans
Male
Mice
Oxygen Consumption - drug effects
Pseudomonas aeruginosa
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Summary:Haemolysin of Pseudomonas aeruginosa exerts toxic effects upon the metabolism of Ehrlich ascitic tumor cells : morphological changes appear readily ; respiration is inhibited more slowly ; the lethal effect determined by intraperitoneal injection of tumor cells is neutralized. Inhibition with human normal sera is complete for the hemolytic action, but incomplete for the cytopathic action.
ISSN:0037-9026