Preparation and testing of polyvalent EDTA-Na-extract vaccine from Escherichia coli strains pathogenic to Swine

Monovalent vaccines were prepared of E. coli strains with pathogenicity to swine by means of a technique described elsewhere. A polyvalent vaccine was obtained by mixing the monovalent vaccines. This polyvalent vaccine was tested by criteria usually applied to vaccine of E. coli strains with pathoge...

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Bibliographic Details
Published inArchiv fur experimentelle Veterinarmedizin Vol. 33; no. 1; p. 47
Main Authors Austenat, L, Hering, L, Grahlow, W D, Rockstroh, T
Format Journal Article
LanguageGerman
Published Germany 01.01.1979
Subjects
Animals
Bacterial Vaccines - immunology
Bacterial Vaccines - isolation & purification
Bacterial Vaccines - toxicity
Dose-Response Relationship, Immunologic
Drug Evaluation, Preclinical - veterinary
Edetic Acid
Escherichia coli - immunology
Escherichia coli - pathogenicity
Lethal Dose 50
Mice
Sodium
Swine - immunology
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Summary:Monovalent vaccines were prepared of E. coli strains with pathogenicity to swine by means of a technique described elsewhere. A polyvalent vaccine was obtained by mixing the monovalent vaccines. This polyvalent vaccine was tested by criteria usually applied to vaccine of E. coli strains with pathogenicity to man, and it exhibited the same quality characteristics.
ISSN:0003-9055