Use of and adherence to antiretroviral therapy is associated with decreased sexual risk behavior in HIV clinic patients

Previous research suggested that the availability of highly active antiretroviral therapy (ART) was associated with increased risky sexual behavior. This study examined the relationship between unprotected anal or vaginal sex (UAV) and ART use and adherence in a cross-sectional survey conducted in 8...

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Bibliographic Details
Published inJournal of acquired immune deficiency syndromes (1999) Vol. 39; no. 2; p. 211
Main Authors Diamond, Catherine, Richardson, Jean L, Milam, Joel, Stoyanoff, Susan, McCutchan, J Allen, Kemper, Carol, Larsen, Robert A, Hollander, Harry, Weismuller, Penny, Bolan, Robert
Format Journal Article
LanguageEnglish
Published United States 01.06.2005
Subjects
Adult
Aged
Anti-HIV Agents - administration & dosage
Anti-HIV Agents - therapeutic use
California
Continental Population Groups
Depression - epidemiology
Female
Health Behavior
HIV Infections - drug therapy
HIV Infections - psychology
Homosexuality, Male
Humans
Male
Middle Aged
Patient Compliance
Retrospective Studies
Risk-Taking
Safe Sex - psychology
Sexual Behavior
California
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Summary:Previous research suggested that the availability of highly active antiretroviral therapy (ART) was associated with increased risky sexual behavior. This study examined the relationship between unprotected anal or vaginal sex (UAV) and ART use and adherence in a cross-sectional survey conducted in 874 randomly selected, sexually active patients at 6 public HIV clinics in California. Patients completed a standardized interview in 1998-1999 regarding HIV history, sexual behavior, illicit drug use, and ART use and adherence. Thirty-four percent reported UAV, defined as anal or vaginal sex without a condom within the past 3 months. Of 79% on ART, 26% reported <95% adherence. Decreased odds for UAV were found for both ART use, odds ratio (OR) 0.5 (95% CI 0.4-0.7, P < 0.001) and adherence to ART of > or = 95%, OR 0.6 (95% CI 0.4-0.8, P < 0.001). These relationships persisted in most stratified analysis for both ART use and adherence but in multivariate analysis only for ART use. An undetectable HIV RNA was associated with decreased odds of UAV, OR 0.6 (95% CI 0.5-0.8, P < 0.001). Contrary to expectations, use of and adherence to ART and their consequent suppression of HIV were associated with a decreased prevalence of self-reported risky sexual behavior.
ISSN:1525-4135
DOI:10.1097/01.qai.0000143602.87104.d9