The Effect of Menopausal Hormone Therapies on Breast Cancer: Avoiding the Risk

Estrogen and P treatment results in greater risk of breast cancer than placebo. Treatment with estrogen alone does not increase the risk of breast cancer, may be used by women who have had a hysterectomy, and may even result in a decreased risk of breast cancer. Continued research seeks to improve t...

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Bibliographic Details
Published inEndocrinology and metabolism clinics of North America Vol. 44; no. 3; p. 587
Main Authors Flores, Valerie A, Taylor, Hugh S
Format Journal Article
LanguageEnglish
Published United States 01.09.2015
Subjects
Breast Neoplasms - chemically induced
Estrogen Replacement Therapy - adverse effects
Female
Humans
Menopause
Risk Factors
Breast cancer
Hormone therapy
Estrogens
Menopause
Progestogen
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Summary:Estrogen and P treatment results in greater risk of breast cancer than placebo. Treatment with estrogen alone does not increase the risk of breast cancer, may be used by women who have had a hysterectomy, and may even result in a decreased risk of breast cancer. Continued research seeks to improve the understanding of the interplay between estrogen and progestogens that predispose to adverse effects on breast tissue. Caution over this hypothesized benefit is warranted until it is substantiated by data on the incidence of breast cancer in tissue selective estrogen complex users.
ISSN:1558-4410
DOI:10.1016/j.ecl.2015.05.007