Successful use of combination antifungal therapy in the treatment of coccidioides meningitis

Coccidioidal meningitis is a highly lethal condition with a high morbidity and relapse rate caused by Coccidioides immitis. This case report highlights the difficulty in diagnosing and treating coccidioidal meningitis, and discusses a novel combination antifungal therapy (voriconazole and liposomal...

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Bibliographic Details
Published inJournal of the National Medical Association Vol. 98; no. 6; pp. 940 - 942
Main Authors ANTONY, Suresh J, JURCZYK, Peter, BRUMBLE, Lisa
Format Journal Article
LanguageEnglish
Published Thorofare, NJ Slack 01.06.2006
Elsevier Limited
National Medical Association
Subjects
Adult
Amphotericin B - therapeutic use
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antifungal agents
Antifungal Agents - therapeutic use
Biological and medical sciences
Coccidioides - drug effects
Coccidioides - isolation & purification
Coccidioidomycosis - diagnosis
Coccidioidomycosis - drug therapy
Diagnosis, Differential
Drug Therapy, Combination
General aspects
Humans
Male
Medical sciences
Meningitis, Fungal - diagnosis
Meningitis, Fungal - drug therapy
Pharmacology. Drug treatments
Pyrimidines - therapeutic use
Triazoles - therapeutic use
Voriconazole
treatment
Nervous system diseases
Drug combination
Coccidioides immitis
Use
Phycomycetes
Fungi
Antifungal agent
Central nervous system disease
Tropical medicine
Meningitis
Combined treatment
Thallophyta
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Summary:Coccidioidal meningitis is a highly lethal condition with a high morbidity and relapse rate caused by Coccidioides immitis. This case report highlights the difficulty in diagnosing and treating coccidioidal meningitis, and discusses a novel combination antifungal therapy (voriconazole and liposomal amphotericin B), which was used to treat this patient.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
content type line 23
ObjectType-Report-1
ObjectType-Article-3
ISSN:0027-9684
1943-4693