Single cell analysis revealed a coexistence of NOTCH1 and TP53 mutations within the same cancer cells in chronic lymphocytic leukaemia patients

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Bibliographic Details
Published inBritish journal of haematology Vol. 178; no. 6; pp. 979 - 982
Main Authors Kantorova, Barbara, Malcikova, Jitka, Brazdilova, Kamila, Borsky, Marek, Plevova, Karla, Smardova, Jana, Radova, Lenka, Tom, Nikola, Trbusek, Martin, Diviskova, Eva, Francova, Hana Skuhrova, Navrkalova, Veronika, Doubek, Michael, Brychtova, Yvona, Mayer, Jiri, Pospisilova, Sarka
Format Journal Article
LanguageEnglish
Published England Blackwell Publishing Ltd 01.09.2017
Subjects
Alleles
Cancer
Chronic lymphocytic leukemia
CLL
clonal evolution
Clonal Evolution - genetics
DNA Mutational Analysis - methods
Genotype
Hematology
Humans
Leukemia
Leukemia, Lymphocytic, Chronic, B-Cell - diagnosis
Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy
Leukemia, Lymphocytic, Chronic, B-Cell - genetics
NOTCH1 mutation
Notch1 protein
p53 Protein
Receptor, Notch1 - genetics
single cell analysis
Single-Cell Analysis - methods
TP53 mutations
Tumor Suppressor Protein p53 - genetics
CLL
TP53 mutations
clonal evolution
single cell analysis
NOTCH1 mutation
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Bibliography:SourceType-Other Sources-1
ObjectType-Article-2
content type line 63
ObjectType-Correspondence-1
ISSN:0007-1048
1365-2141
DOI:10.1111/bjh.14176