Synthesis of triphenylpyridines via an oxidative cyclization reaction using Sr-doped LaCoO3 perovskite as a recyclable heterogeneous catalyst

• Published in: RSC advances Vol. 9; no. 41; pp. 23876 - 23887
• Main Authors: Le, Thu N M, Doan, Son H, Pham, Phuc H, Trinh, Khang H, Huynh, Tien V, Tran, Tien T T, Le, Minh-Vien, Nguyen, Tung T, Phan, Nam T S
• Format: Journal Article
• Language: English
• Published: Cambridge Royal Society of Chemistry 2019; The Royal Society of Chemistry
• Subjects: Catalysis; Catalysts; Chemical synthesis; Chemistry; Gelation; Hydrogen bonds; Lanthanum; Lanthanum strontium cobaltous oxide; Perovskites; Phenylacetic acid; Strontium
• ISSN: 2046-2069; 2046-2069
• DOI: 10.1039/c9ra04096j

An La0.6Sr0.4CoO3 strontium-doped lanthanum cobaltite perovskite was prepared via a gelation and calcination approach and used as a heterogeneous catalyst for the synthesis of triphenylpyridines via the cyclization reaction between ketoximes and phenylacetic acids. The transformation proceeded via the oxidative functionalization of the sp3 C–H bond in phenylacetic acid. The La0.6Sr0.4CoO3 catalyst demonstrated a superior performance to that of the pristine LaCoCO3 as well as a series of homogeneous and heterogeneous catalysts. Furthermore, the La0.6Sr0.4CoO3 catalyst was facilely recovered and reused without considerable decline in its catalytic efficiency. To the best of our knowledge, the combination of ketoximes with easily available phenylacetic acids is novel.