Mass spectrometry for the study of autism and neurodevelopmental disorders

• Published in: Advances in experimental medicine and biology Vol. 806; p. 525
• Main Authors: Ngounou Wetie, Armand G, Dekroon, Robert M, Mocanu, Mihaela, Ryan, Jeanne P, Darie, Costel C, Woods, Alisa G
• Format: Journal Article
• Language: English
• Published: United States 01.01.2014
• Subjects: Animals; Autistic Disorder - metabolism; Fragile X Syndrome - metabolism; Humans; Mass Spectrometry - methods; Proteomics - methods; Smith-Lemli-Opitz Syndrome - metabolism
• ISSN: 0065-2598
• DOI: 10.1007/978-3-319-06068-2_26

Mass spectrometry (MS) has been increasingly used to study central nervous system disorders, including autism spectrum disorders (ASDs). The first studies of ASD using MS focused on the identification of external toxins, but current research is more directed at understanding endogenous protein chang...