Magnetic resonance demonstration of normal CSF flow

• Published in: American journal of neuroradiology : AJNR Vol. 7; no. 1; pp. 3 - 6
• Main Authors: SHERMAN, J. L, CITRIN, C. M
• Format: Journal Article
• Language: English
• Published: Oak Brook, IL American Society of Neuroradiology 1986
• Subjects: Adult; Aged; Biological and medical sciences; Brain - physiology; Cerebral Aqueduct - physiology; Cerebral Ventricles - physiology; Cerebrospinal Fluid - physiology; Female; Humans; Investigative techniques, diagnostic techniques (general aspects); Magnetic Resonance Spectroscopy; Male; Medical sciences; Middle Aged; Nervous system; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Retrospective Studies; Human; Nervous system diseases; Circulation of the cerebrospinal fluid; Brain (Vertebrata); Normal; Nuclear magnetic resonance imaging; Biomedical engineering
• ISSN: 0195-6108; 1936-959X

The magnetic resonance (MR) imaging appearance and incidence of flowing cerebrospinal fluid (CSF) in the brain were investigated. The MR scans of 46 randomly selected patients with normal examinations were retrospectively reviewed. All patients were studied using both T2-weighted and T1-weighted spin-echo pulse sequences. Thirty-one patients (67%) had decreased intensity in the aqueduct of Sylvius on the T2-weighted images when compared with the intensity of CSF in the lateral ventricles. This was termed the CSF flow-void sign. The feature was present in the caudal fourth ventricle in 15 patients (32%) and in the third ventricle in two patients (4%) on T2-weighted scans. It was seen in only 13% of patients on T1-weighted scans. It is believed the CSF flow-void sign represents pulsatile CSF flow. Its recognition is important because it explains the inhomogeneity in the appearance of the CSF, which could be confused with pathologic processes. It may be valuable in the routine evaluation of MR examinations if it does reflect CSF circulatory dynamics.