Flagellar Hook/Needle Length Control and Secretion Control in Type III Secretion Systems
The flagellum is a motile organ, and the needle complex is a type III secretion apparatus for pathogenesis. There are more similarities than differences between the two structures at the molecular level. Here I focus on the hook and the needle and discuss their length control mechanism. The hook is...
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| Published in | Current topics in microbiology and immunology |
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| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
Germany
01.01.2020
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| Online Access | Get more information |
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| Summary: | The flagellum is a motile organ, and the needle complex is a type III secretion apparatus for pathogenesis. There are more similarities than differences between the two structures at the molecular level. Here I focus on the hook and the needle and discuss their length control mechanism. The hook is a substructure of the flagellum and the needle is a part of the needle complex. Both structures are tubular structures that have a central channel for protein secretion. Their lengths are controlled by an intriguing mechanism involving a ruler protein and a switchable gate of the protein secretion system. A model for length control is proposed. |
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| ISSN: | 0070-217X |
| DOI: | 10.1007/82_2019_169 |