African-American heredity prostate cancer study: a model for genetic research

• Published in: Journal of the National Medical Association Vol. 93; no. 12 Suppl; pp. 25S - 28S
• Main Authors: Powell, I J, Carpten, J, Dunston, G, Kittles, R, Bennett, J, Hoke, G, Pettaway, C, Weinrich, S, Vijayakumar, S, Ahaghotu, C A, Boykin, W, Mason, T, Royal, C, Baffoe-Bonnie, A, Bailey-Wilson, J, Berg, K, Trent, J, Collins, F
• Format: Journal Article
• Language: English
• Published: United States Elsevier Limited 01.12.2001; National Medical Association
• Subjects: Black or African American; Black People - genetics; Human Genome Project; Humans; Male; Middle Aged; Patient Selection; Prostatic Neoplasms - ethnology; Prostatic Neoplasms - genetics; United States; United States

A genome-wide scan of high-risk prostate cancer families in North America has demonstrated linkage of a particular marker to Chromosome Iq (HPC11. An even greater proportion of African-American families have shown linkage to HPC 1. Therefore, investigators at the National Human Genome Research Insti...