American cranberry (proanthocyanidin 120 mg): its value for the prevention of urinary tracts infections after ureteral catheter placement

• Published in: Actas urologicas españolas Vol. 39; no. 2; pp. 112 - 117
• Main Authors: Barnoiu, O S, Sequeira-García Del Moral, J, Sanchez-Martínez, N, Díaz-Molina, P, Flores-Sirvent, L, Baena-González, V
• Format: Journal Article
• Language: English; Spanish
• Published: Spain 01.03.2015
• Subjects: Adult; Antibiotic Prophylaxis; Catheter-Related Infections - drug therapy; Female; Humans; Male; Middle Aged; Phytotherapy; Plant Extracts - therapeutic use; Proanthocyanidins - therapeutic use; Prospective Studies; Treatment Outcome; Urinary Catheterization - adverse effects; Urinary Tract Infections - drug therapy; Vaccinium macrocarpon; Catéter ureteral doble J; American cranberry; Urinary tract infection; Arándano rojo; Infección de tracto urinario; Double J catheter
• ISSN: 1699-7980
• DOI: 10.1016/j.acuro.2014.07.003

Urinary tract infection (UTI) is among the most frequent complications after urinary tract surgical procedures, mainly when catheter placement is necessary. Although the use of American cranberry has been related with a reduced risk of UTI, there is no study reporting the value of its prevention effect against catheter-associated urinary tract infections. A prospective trial comparing UTI rate (positive urine culture) among 31 patients with double J catheter (JJ) and adding American cranberry (120 mg) in routine prophylactic therapy, and 31 patients with JJ catheter only receiving routine prophylactic therapy. Regarding general characteristics of the populations no significant difference among groups have been found. Only significant differences have been observed when the variables "cranberry treatment" and "dwell time of JJ catheter" were related. "Dwell time of JJ catheter" was higher in patients with UTI (35.9 compared 28.5 days [P=.03]). UTI percentage was lower in cranberry supplemented patient group (12.9 compared to 38.7% [P=.04]). We can conclude that American cranberry (120 mg) has an adjuvant effect in the prevention of UTI in patients with JJ catheter after surgery.