Surgical Aspects of Intraductal Papillary Mucinous Neoplasms of the Pancreas

• Published in: Chirurgia (Bucharest, Romania : 1990) Vol. 110; no. 5; pp. 413 - 417
• Main Authors: Oláh, A, Kollár, D
• Format: Journal Article
• Language: English
• Published: Romania 01.09.2015
• Subjects: Adenocarcinoma, Mucinous - diagnosis; Adenocarcinoma, Mucinous - mortality; Adenocarcinoma, Mucinous - surgery; Carcinoma, Pancreatic Ductal - diagnosis; Carcinoma, Pancreatic Ductal - mortality; Carcinoma, Pancreatic Ductal - surgery; Carcinoma, Papillary - diagnosis; Carcinoma, Papillary - mortality; Carcinoma, Papillary - surgery; Cell Transformation, Neoplastic; Diagnosis, Differential; Early Detection of Cancer; Humans; Hungary - epidemiology; Incidence; Pancreatic Neoplasms - diagnosis; Pancreatic Neoplasms - mortality; Pancreatic Neoplasms - surgery; Risk Factors; Survival Rate; Treatment Outcome; Hungary
• ISSN: 1221-9118

Intraductal papillary mucinous neoplasms (IPMN) play an important role mongst exocrine tumours of the pancreas due to several causes. Although they count for only 1% of all the tumours, they represent some 20-30% of all cystic neoplasms, a histologically defined group that has gained a lot of attention lately. IPMNs of the main or the secondary (branch) pancreatic ducts have remarkably different rates of malignant transformation, prognosis and thus indication for surgery. Prognosis of a ductal carcinoma developing from IPMN does not differ from classic ductal adenocarcinoma, with a very poor (10%) 5-year survival rate. However, prognosis of IPMN can still be regarded favourable, because the above rate can be as high as 70% if the tumour is non-invasive. This fact leads to the importance of diagnosing and resecting IPMN before its malignant transformation into an invasive carcinoma.