Ceftriaxone-Induced Thrombocytopenia in a Patient with Bacterial Meningoencephalitis

Drug-induced thrombocytopenia is a rare and life-threatening condition. It is mainly caused by the initiation of drug-dependent platelet reactive antibodies that leads to the accelerated platelet destruction. Ceftriaxone is a third-generation cephalosporin, which has rarely reported cases of drug-in...

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Bibliographic Details
Published inJournal of pharmacology & pharmacotherapeutics Vol. 12; no. 4; pp. 175 - 176
Main Authors Kumar, Anjaly A., Vijay, Vani, Arya, M., Vasant, P. K., Chandra, Subhash, Menon, Abhishek C.
Format Journal Article
LanguageEnglish
Published New Delhi, India SAGE Publications 01.10.2021
Wolters Kluwer India Pvt. Ltd
Sage Publications Ltd
Subjects
Antibiotics
Encephalitis
Meningitis
Thrombocytopenia
meningoencephalitis
Ceftriaxone
drug-induced immune thrombocytopenia
thrombocytopenia
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Summary:Drug-induced thrombocytopenia is a rare and life-threatening condition. It is mainly caused by the initiation of drug-dependent platelet reactive antibodies that leads to the accelerated platelet destruction. Ceftriaxone is a third-generation cephalosporin, which has rarely reported cases of drug-induced immune thrombocytopenia. Here, we report a case of ceftriaxone-induced thrombocytopenia after the initiation of antibiotic therapy for bacterial meningoencephalitis based on the laboratory findings with the initiation and discontinuation of ceftriaxone.
ISSN:0976-500X
0976-5018
DOI:10.4103/jpp.jpp_106_21