Fibrinolysis and peptic ulcer

The results here presented are well correlated to previous studies showing a low activity of plasminogen activator around an ulcer, but a high activity proximally to this has not been shown before, neither that the activity is dependent on the ulcer localization. The results show low fibrinolytic ac...

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Bibliographic Details
Published inActa chirurgica Scandinavica. Supplementum Vol. 547; p. 39
Main Author Helgstrand, U
Format Journal Article
LanguageEnglish
Published Sweden 1988
Subjects
Biopsy
Cimetidine - therapeutic use
Female
Fibrinolysis
Gastric Mucosa - pathology
Humans
Intestinal Mucosa - pathology
Male
Middle Aged
Peptic Ulcer - pathology
Peptic Ulcer - therapy
Plasminogen Activators - metabolism
Vagotomy, Proximal Gastric
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Summary:The results here presented are well correlated to previous studies showing a low activity of plasminogen activator around an ulcer, but a high activity proximally to this has not been shown before, neither that the activity is dependent on the ulcer localization. The results show low fibrinolytic activity in the mucosa after treatment with cimetidine which has not before been observed. Theoretically these results could give an idea of better effect of antifibrinolytic treatment in patients with bleeding from duodenal ulcer.
ISSN:0301-1860