Human cytomegalovirus gB1 genotypes among children who live at the Phayathai Babies' home in Nonthaburi, Thailand

We conducted a survey of human cytomegalovirus (HCMV) genotypes among 176 children aged 1 month to 5 years living at Phayathai Babies' Home in Nonthaburi Province, Thailand to determine the prevalence of HCMV glycoprotein B (gB) genotype. The study was conducted on urine samples using nested po...

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Published inSoutheast Asian journal of tropical medicine and public health Vol. 44; no. 4; pp. 636 - 640
Main Authors Paca-Uccaralertkun, Saowakon, Hiatt, Rungnapa, Leecharoen, Rujee, Tan-Ariya, Peerapan, Mungthin, Mathirut, Pongphong, Sureeporn
Format Journal Article
LanguageEnglish
Published Thailand Central Coordinating Board, SEAMEO-TROPMED Project 01.07.2013
Subjects
Babies
Child, Preschool
Children
Cytomegalovirus
Cytomegalovirus - genetics
Cytomegalovirus Infections - epidemiology
Cytomegalovirus Infections - genetics
DNA, Viral - genetics
Female
Gene polymorphism
Genotype
Genotypes
Glycoprotein B
Glycoproteins
Human cytomegalovirus
Humans
Infant
Male
Orphanages - statistics & numerical data
Polymerase Chain Reaction
Polymorphism
Polymorphism, Restriction Fragment Length
Prevalence
Restriction fragment length polymorphism
Thailand
Urine
Viral Envelope Proteins - genetics
Thailand
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Summary:We conducted a survey of human cytomegalovirus (HCMV) genotypes among 176 children aged 1 month to 5 years living at Phayathai Babies' Home in Nonthaburi Province, Thailand to determine the prevalence of HCMV glycoprotein B (gB) genotype. The study was conducted on urine samples using nested polymerase chain reaction and restriction fragment length polymorphism; the HCMV gB1 genotype was found in 89% of subjects, much higher than previous reports. Our results show a high proportion of HCMV gB1 infected children in this population.
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SourceType-Scholarly Journals-1
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ISSN:0125-1562