Post-thyroidectomy complications. The role of the device: bipolar vs ultrasonic device: Collection of data from 1,846 consecutive patients undergoing thyroidectomy

• Published in: The American journal of surgery Vol. 212; no. 1; pp. 116 - 121
• Main Authors: De Palma, Maurizio, Rosato, Ludovico, Zingone, Fabiana, Orlando, Giulio, Antonino, Antonio, Vitale, Mario, Puzziello, Alessandro
• Format: Journal Article
• Language: English
• Published: United States Elsevier Limited 01.07.2016
• Subjects: Adult; Age; Aged; Cohort Studies; Confidence Intervals; Female; Follow-Up Studies; Humans; Hypocalcemia - etiology; Hypocalcemia - physiopathology; Hypoparathyroidism - etiology; Hypoparathyroidism - physiopathology; Incidence; Injuries; Italy; Male; Middle Aged; Mortality; Odds Ratio; Postoperative Complications - epidemiology; Postoperative Complications - physiopathology; Prospective Studies; Risk Assessment; Role; Surgery; Surgical Instruments - adverse effects; Thyroid diseases; Thyroid Diseases - pathology; Thyroid Diseases - surgery; Thyroidectomy - adverse effects; Thyroidectomy - instrumentation; Thyroidectomy - methods; Ultrasonic Surgical Procedures - adverse effects; Ultrasonic Surgical Procedures - methods; Variables; Vocal Cord Paralysis - etiology; Vocal Cord Paralysis - physiopathology; Young Adult; RLN palsy; Ultrasonic device; Thyroidectomy; Bipolar forceps; Hypocalcemia
• ISSN: 0002-9610; 1879-1883
• DOI: 10.1016/j.amjsurg.2015.05.024

Specific complications after thyroid surgery, such as recurrent laryngeal nerve injury (RLN) or hypoparathyroidism, are feared because they may give rise to a lifelong disability for the patient. The aim of this study was to evaluate the possible association between the types of device used (bipolar vs ultrasound-based harmonic scalpel defined Harmonic Focus) and major postoperative complications. During a 1-year period, between October 2010 and October 2011, Italian Endocrine Surgery Units affiliated with the Italian Endocrine Surgery Units Association collected data on all consecutive patients older than 18 years who had undergone primary total thyroidectomy, near total thyroidectomy, and completion thyroidectomy. The data were included in a dataset, listing demographic variables, details on the surgical procedure, and 2 major complications of the thyroid surgery: postoperative RLN palsy/hypomobility and hypocalcemia. Our population comprised 1,846 subjects (78.6% women, median age 52 years). Six hundred four (32.7%) subjects underwent thyroidectomy by bipolar forceps and 1,242 (67.3%) by ultrasonic device. The risk of hypocalcemia in subjects undergoing thyroidectomy by ultrasonic device was similar to those undergoing thyroidectomy by bipolar after adjusting for sex, type of thyroidectomy, and central lymphadenectomy (odds ratio .94, 95% confidence interval .76 to 1.17). Subjects who underwent thyroidectomy by ultrasonic device had a lower risk of RLN paralysis compared with those undergoing thyroidectomy by bipolar forceps also after adjusting for central lymphadenectomy (odds ratio .39, 95% confidence interval .2 to .7). This multicenter study acknowledges the value of the ultrasonic device as a protective factor only for RLN palsy, confirming nodal dissection as a risk factor for postoperative hypocalcemia and vocal folds disorders.