Outcome in recipients of dual kidney transplants: an analysis of the dual registry patients

• Published in: Transplantation Vol. 69; no. 2; p. 281
• Main Authors: Lu, A D, Carter, J T, Weinstein, R J, Stratta, R J, Taylor, R J, Bowers, V D, Ratner, L E, Chavin, K D, Johnson, L B, Kuo, P C, Cole, E H, Dafoe, D C, Alfrey, E J
• Format: Journal Article
• Language: English
• Published: United States 27.01.2000
• Subjects: Aged; Humans; Kidney Transplantation - methods; Kidney Transplantation - physiology; Middle Aged; Registries; Tissue Donors; Treatment Outcome
• ISSN: 0041-1337
• DOI: 10.1097/00007890-200001270-00014

A novel but controversial method to increase the utilization of aged donor kidneys is the transplantation of both kidneys as a dual transplant. Initial single-center reports demonstrated outcomes similar to single kidneys from younger donors. In this report, we compare outcome in recipients of kidneys from donors > or =54 years of age who received a single kidney transplant reported to the United Network for Organ Sharing Scientific Registry versus a dual kidney transplant reported to the Dual Kidney Registry. A retrospective analysis was performed, comparing four donor and nine recipient and outcome variables between recipients of a single versus a dual transplant between March 1993 and March 1999. Dual versus single transplants from donors > or =54 years of age have a significantly decreased incidence of delayed graft function, and lower serum creatinines up to 2 years after transplant despite having kidneys from significantly older donors with poorer HLA matching. Dual kidney transplants improve graft performance and outcome in recipients of kidneys from donors > or =54 years of age.