Mitotic Antipairing of Homologous Chromosomes

Chromosome organization is highly dynamic and plays an essential role during cell function. It was recently found that pairs of the homologous chromosomes are continuously separated at mitosis and display a haploid (1n) chromosome set, or "antipairing," organization in human cells. Here, w...

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Bibliographic Details
Published inResults and problems in cell differentiation Vol. 70; p. 191
Main Authors Hua, Lisa L, Casas, Christian J, Mikawa, Takashi
Format Journal Article
LanguageEnglish
Published Germany 2022
Subjects
Chromosomes
Humans
Mitosis
Antipairing
Homologous chromosomes
Mitosis
Nuclear organization
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Summary:Chromosome organization is highly dynamic and plays an essential role during cell function. It was recently found that pairs of the homologous chromosomes are continuously separated at mitosis and display a haploid (1n) chromosome set, or "antipairing," organization in human cells. Here, we provide an introduction to the current knowledge of homologous antipairing in humans and its implications in human disease.
ISSN:0080-1844
DOI:10.1007/978-3-031-06573-6_6