Treatment of abdominal aortic aneurysms associated with pancreatic tumors : personal experience and review of the literature (1967-2006)

• Published in: International angiology Vol. 27; no. 6; pp. 539 - 542
• Main Authors: VERALDI, G. F, MINICOZZI, A. M, BERNINI, M, GENCO, B, TEDESCHI, U
• Format: Journal Article
• Language: English
• Published: Torino Minerva Medica 01.12.2008; Edizioni Minerva Medica
• Subjects: Aged; Aortic Aneurysm, Abdominal - complications; Aortic Aneurysm, Abdominal - surgery; Biological and medical sciences; Blood and lymphatic vessels; Blood Vessel Prosthesis Implantation - adverse effects; Cardiology. Vascular system; Chemotherapy, Adjuvant; Diseases of the aorta; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous; Humans; Male; Medical sciences; Middle Aged; Neoplasm Staging; Pancreatectomy - adverse effects; Pancreatic Neoplasms - complications; Pancreatic Neoplasms - pathology; Pancreatic Neoplasms - surgery; Patient Selection; Risk Assessment; Risk Factors; Treatment Outcome; Pancreatic tumor; Aortic aneurysms abdominal; Treatment; Comorbidity; Pancreas cancer; Digestive diseases; Cardiovascular disease; Malignant tumor; Aortic aneurysm; Pancreatic neoplasms; Cancer; Pancreatic disease
• ISSN: 0392-9590; 1827-1839

The aim of the present study was to discuss the approach to a rare, but challenging, clinical situation: the coexistence of an abdominal aortic aneurysm (AAA) and a pancreatic tumor. The authors present their experience and a review of the literature of the last 40 years. From January 1988 to December 2006 the authors faced 3 cases of associated AAA and pancreatic neoplasia. Through a Medline search the authors found 15 cases of this comorbidity reported in the literature from 1967 to 2006, obtaining a total number of 18 cases. The treatment of the two diseases was in a single stage in 4 cases (22%) and in two stages in 5 cases (28%), while only one pathology was treated in 7 cases (39%) and no treatment at all was attempted in 2 cases (11%). Mortality was 0%, while morbidity was 22%, i.e. in 4 cases out of 18, although no aortic prosthesis infection was recorded. From literature analysis and their experience the authors concluded that the surgical strategy in cases of AAA and a pancreatic tumor is to be chosen depending on the pancreatic tumor prognosis, the AAA dimensions and the schedule of chemotherapy. According to the authors, AAA surgical repair is recommended in case of pancreatic cystic adenoma and neuroendocrine neoplasia, in view of their good prognosis, while endovascular repair (EVAR), when feasible, is better in patients with pancreatic adenocarcinoma.