Chitosan based hydrogels: characteristics and pharmaceutical applications

Hydrogel scaffolds serve as semi synthetic or synthetic extra cellular matrix to provide an amenable environment for cellular adherence and cellular remodeling in three dimensional structures mimicking that of natural cellular environment. Additionally, hydrogels have the capacity to carry small mol...

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Bibliographic Details
Published inResearch in pharmaceutical sciences Vol. 10; no. 1; pp. 1 - 16
Main Authors Ahmadi, F, Oveisi, Z, Samani, S Mohammadi, Amoozgar, Z
Format Journal Article
LanguageEnglish
Published Iran Medknow Publications & Media Pvt Ltd 01.01.2015
Subjects
Review
Crosslinking
Drug delivery
Chitosan
Hydrogel
Tissue engineering
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Summary:Hydrogel scaffolds serve as semi synthetic or synthetic extra cellular matrix to provide an amenable environment for cellular adherence and cellular remodeling in three dimensional structures mimicking that of natural cellular environment. Additionally, hydrogels have the capacity to carry small molecule drugs and/or proteins, growth factors and other necessary components for cell growth and differentiation. In the context of drug delivery, hydrogels can be utilized to localize drugs, increase drugs concentration at the site of action and consequently reduce off-targeted side effects. The current review aims to describe and classify hydrogels and their methods of production. The main highlight is chitosan-based hydrogels as biocompatible and medically relevant hydrogels for drug delivery.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ObjectType-Review-1
ISSN:1735-5362
1735-9414