Membranous glomerulonephritis and cellular crescents induced by levamisole-adulterated cocaine abuse: a case report

Levamisole is illicitly employed as a cocaine adulterant. The consumption of levamisole-adulterated cocaine can provoke anti-neutrophil cytoplasmic antibody (ANCA)-associated syndromes. Patients carrying an HLAB27 allele are known to be at higher risk of developing agranulocytosis when treated with...

Full description

Saved in:
Bibliographic Details
Published inAnnals of translational medicine Vol. 3; no. 18; p. 271
Main Authors Roca-Argente, Lourdes, Moll-Guillen, Jose-Luis, Espí-Reig, Jordi, Blanes-Julia, Marino, García-Martínez, Ana-María, Pujol-Marco, Conrad, Hernández-Jaras, Julio
Format Journal Article
LanguageEnglish
Published China AME Publishing Company 01.10.2015
Subjects
Case Report
Vasculitis
glomerulonephritis
cocaine
levamisole
anti-neutrophil cytoplasmic antibody (ANCA)
Online AccessGet full text

Cover

More Information
Summary:Levamisole is illicitly employed as a cocaine adulterant. The consumption of levamisole-adulterated cocaine can provoke anti-neutrophil cytoplasmic antibody (ANCA)-associated syndromes. Patients carrying an HLAB27 allele are known to be at higher risk of developing agranulocytosis when treated with levamisole. Likewise, patients with ANCA-associated vasculitis (AAV) and internal organ involvement have typically been exposed to offending agents for prolonged periods of time, often on the order of years. Here, we report an unusual case of a patient in which kidney biopsy showed membranous glomerulonephritis with cellular crescents associated with levamisole-contaminated cocaine use.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:2305-5839
2305-5839
DOI:10.3978/j.issn.2305-5839.2015.10.29