Amiodarone in treatment of fetal supraventricular tachycardia : A case report and review of literature

• Published in: Fetal diagnosis and therapy Vol. 21; no. 1; pp. 72 - 76
• Main Authors: PRADHAN, Mandakini, MANISHA, SINGH, Renu, KAPOOR, Aditya
• Format: Journal Article
• Language: English
• Published: Freiburg Karger 01.01.2006; Basel S. Karger AG; Paris
• Subjects: Adult; Amiodarone - therapeutic use; Anti-Arrhythmia Agents - therapeutic use; Biological and medical sciences; Cardiac dysrhythmias; Cardiology. Vascular system; Digoxin - therapeutic use; Drug Therapy, Combination; Echocardiography, Doppler; Female; Fetal Diseases - diagnostic imaging; Fetal Diseases - drug therapy; Gynecology. Andrology. Obstetrics; Heart; Humans; Hydrops Fetalis - diagnosis; Hydrops Fetalis - etiology; Management. Prenatal diagnosis; Maternal-Fetal Exchange; Medical sciences; Pregnancy; Pregnancy. Fetus. Placenta; Tachycardia, Supraventricular - complications; Tachycardia, Supraventricular - diagnostic imaging; Tachycardia, Supraventricular - drug therapy; Ultrasonography, Prenatal; Pregnancy disorders; Arrhythmia; Prenatal Diagnosis; Cardiovascular disease; Amiodarone; Review; Paroxysmal supraventricular tachycardia; Iodine Organic compounds; Excitability disorder; Case study; Fetal diseases; Treatment; Hydrops fetalis; Heart disease; Fetal supraventricular tachycardia; Bibliographic review
• ISSN: 1015-3837; 1421-9964
• DOI: 10.1159/000089052

We report a case of nonimmune hydrops fetalis detected at 32 weeks of gestation. Fetal heart rate was 300 beats per minute. Ultrasound and fetal Doppler echocardiography showed it to be due to supraventricular tachycardia (SVT). Following failed maternal therapy with digoxin alone, amiodarone with digoxin was used. Conversion to sinus rhythm and resolution of hydrops followed this treatment. Since there is no ideal treatment protocol for these cases at present, we reviewed reports of transplacental treatment of SVT.