Validated Liquid Culture Monitoring System for Lifespan Extension of Caenorhabditis elegans through Genetic and Dietary Manipulations

• Published in: Aging and disease Vol. 4; no. 4; pp. 178 - 185
• Main Authors: Win, Myat Thu Thu, Yamamoto, Yasuhiko, Munesue, Seiichi, Han, Dong, Harada, Shin-Ichi, Yamamoto, Hiroshi
• Format: Journal Article
• Language: English
• Published: United States JKL International LLC 01.08.2013
• Subjects: Original; C. elegans; caloric restriction; aging; lifespan

Nutritional and genetic factors influence aging and life expectancy. The reduction of food intake without malnutrition, referred to caloric restriction (CR), has been shown to increase lifespan in a wide variety of species. The nematode Caenorhabditis elegans (C. elegans) is one of the principle mod...