Macrotetrolide antibiotics produced by Streptomyces globisporus

Macrotetrolides isolated from a new producer, Streptomyces globisporus, were identified as nonactin, monactin, dinactin and trinactin. Spectroscopic characterization of these compounds was extended by 13NMR spectra. Chemical ionization with ammonia as reactive gas was proposed for mass-spectroscopic...

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Bibliographic Details
Published inFolia microbiologica Vol. 36; no. 5; p. 437
Main Authors Jizba, J, Sedmera, P, Zima, J, Beran, M, Blumauerová, M, Kandybin, N V, Samoukina, G V
Format Journal Article
LanguageEnglish
Published United States 01.01.1991
Subjects
Animals
Anti-Bacterial Agents - biosynthesis
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - pharmacology
Coleoptera
Insecticides - chemistry
Insecticides - metabolism
Macrolides
Molecular Structure
Pest Control, Biological
Streptomyces - metabolism
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Summary:Macrotetrolides isolated from a new producer, Streptomyces globisporus, were identified as nonactin, monactin, dinactin and trinactin. Spectroscopic characterization of these compounds was extended by 13NMR spectra. Chemical ionization with ammonia as reactive gas was proposed for mass-spectroscopic characterization of their mixtures. Their biological activity was confirmed by using larvae of the Colorado potato beetle (Leptinotarsa decemlineata) as a new test model.
ISSN:0015-5632
DOI:10.1007/BF02884062