The atypical lipopolysaccharide of Francisella

Bacterial lipopolysaccharides (LPSs) are ubiquitous molecules that are prominent components of the outer membranes of most gram-negative bacteria. Genetic and structural characterizations of Francisella LPS have revealed substantial differences when compared to more commonly studied LPSs of the Ente...

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Bibliographic Details
Published inCarbohydrate research Vol. 378; pp. 79 - 83
Main Authors Okan, Nihal A, Kasper, Dennis L
Format Journal Article
LanguageEnglish
Published Netherlands 30.08.2013
Subjects
Francisella - metabolism
Lipid A - biosynthesis
Lipid A - chemistry
Lipid A - metabolism
Lipopolysaccharides - biosynthesis
Lipopolysaccharides - chemistry
Lipopolysaccharides - metabolism
O Antigens - biosynthesis
O Antigens - chemistry
O Antigens - metabolism
2-acetamido-2,6-dideoxy-d-glucose
3-deoxy-d-manno-octulosonic acid
4,6-dideoxy-4-formamido-d-glucose
Qui4NFm
O-antigen
Qui2NAc4NAc
Kdo hydrolase
GalNAcAN
LPS
Lipid A
QuiNAc
Lipopolysachharide
Kdo
2,4-diacetamido-2,4,6-trideoxy-d-glucose
2-acetamido-2-deoxy-d-galacturonamide
Structure
Francisella tularensis
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Summary:Bacterial lipopolysaccharides (LPSs) are ubiquitous molecules that are prominent components of the outer membranes of most gram-negative bacteria. Genetic and structural characterizations of Francisella LPS have revealed substantial differences when compared to more commonly studied LPSs of the Enterobacteriaceae. This review discusses both the general characteristics and the unusual features of Francisella LPS.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0008-6215
1873-426X
DOI:10.1016/j.carres.2013.06.015