Cross reactions among serogroup B meningococci assayed by kinetic complement fixation assay

The surface antigens of five prototype serogroup B strains were investigated by a rapid turbido-haemolytic complement fixation assay. Several cross-reactions among the serotypes were detected. It is suggested that antigenic determinants accessible for antigen-antibody interaction need not be immunog...

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Bibliographic Details
Published inMicrobios Vol. 48; no. 196-197; p. 183
Main Authors DiNinno, V L, Bhatti, A R, White, L A
Format Journal Article
LanguageEnglish
Published England 1986
Subjects
Antigens, Bacterial - immunology
Antigens, Surface - immunology
Complement Fixation Tests
Cross Reactions
Epitopes - immunology
Neisseria meningitidis - classification
Neisseria meningitidis - immunology
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Summary:The surface antigens of five prototype serogroup B strains were investigated by a rapid turbido-haemolytic complement fixation assay. Several cross-reactions among the serotypes were detected. It is suggested that antigenic determinants accessible for antigen-antibody interaction need not be immunogenic.
ISSN:0026-2633