Inherited bleeding disorders: results from the Italian Regional Haemophilia Centre of Pescara

Inherited bleeding disorders registries can be useful to improve health care of these rare disorders and document their natural history. We analysed the epidemiological, diagnostic and therapeutic aspects of patients managed at an Italian Regional Haemophilia Centre, based in Pescara (in the Region...

Full description

Saved in:
Bibliographic Details
Published inBlood transfusion = Trasfusione del sangue Vol. 6; no. 3; pp. 136 - 142
Main Authors Dragani, Alfredo, Malizia, Raniero, Iuliani, Ornella, Di Marzio, Ilaria, Davì, Giovanni
Format Journal Article
LanguageEnglish
Published Italy Edizioni SIMTI - SIMTI Servizi Srl 01.07.2008
Subjects
Adolescent
Adult
Blood Coagulation Disorders, Inherited - epidemiology
Blood Coagulation Disorders, Inherited - genetics
Blood Coagulation Disorders, Inherited - therapy
Blood Component Transfusion - statistics & numerical data
Child
Child, Preschool
Genetic Predisposition to Disease - genetics
Humans
Infant
Italy - epidemiology
Middle Aged
Original
Polymorphism, Single Nucleotide - genetics
Registries
Italy
Online AccessGet full text

Cover

More Information
Summary:Inherited bleeding disorders registries can be useful to improve health care of these rare disorders and document their natural history. We analysed the epidemiological, diagnostic and therapeutic aspects of patients managed at an Italian Regional Haemophilia Centre, based in Pescara (in the Region of Abruzzo). This Regional Haemophilia Centre currently follows 376 patients: 248 with rare clotting factor defects, 33 with von Willebrand's disease, 75 with haemophilia A and 20 with haemophilia B. Three patients with severe haemophilia A have developed inhibitors. Among all the haemophiliacs, the prevalence of hepatitis C virus infection is 21% while the prevalence of human immunodeficiency virus infection is 5.3%. Among the whole haemophilic population referring to the Pescara Haemophilia Centre, 87.4% are treated with recombinant factors while 12 patients with severe haemophilia are receiving primary prophylaxis. In brief, an analysis of the epidemiological, clinical and therapeutic data collected at the Regional Haemophilia Centre of Pescara is a useful tool for monitoring and continuously improving the quality of care of patients with inherited bleeding disorders.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1723-2007
DOI:10.2450/2008.0050-07