Exercise and activity level in Alzheimer's disease : A potential treatment focus

• Published in: Journal of rehabilitation research and development Vol. 35; no. 4; pp. 411 - 419
• Main Authors: TERI, L, MCCURRY, S. M, BUCHNER, D. M, LOGSDON, R. G, LACROIX, A. Z, KUKULL, W. A, BARLOW, W. E, LARSON, E. B
• Format: Journal Article
• Language: English
• Published: Baltimore, MD Rehabilitation Research and Development Service 01.10.1998; Superintendent of Documents
• Subjects: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Alzheimer Disease - physiopathology; Alzheimer Disease - psychology; Alzheimer Disease - rehabilitation; Alzheimer's disease; Biological and medical sciences; Caregivers - education; Community Health Services; Diseases of the nervous system; Exercise; Exercise Therapy - methods; Female; Geriatric Assessment; Health Status; Home Nursing; Humans; Male; Medical sciences; Middle Aged; Patient Compliance; Physical Endurance; Program Evaluation; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects); Rehabilitation; Physical exercise; Human; Nervous system diseases; Alzheimer disease; Caregiver; Motive force; Physical rehabilitation; Equilibrium; Cerebral disorder; Result; Central nervous system disease; Dragging; Treatment compliance; Degenerative disease; Rehabilitation
• ISSN: 0748-7711; 1938-1352

This article provides information on the baseline health and physical function of 30 individuals with Alzheimer's disease (AD); describes a community-based program designed to increase balance, flexibility, strength, and endurance in these persons by the training of caregivers to facilitate and supervise exercise activity; and documents the adherence of these subjects and their caregivers to this intervention. Subjects were recruited from an ongoing, community-based Alzheimer's Disease Patient Registry, and met NINCDS-ADRDA criteria for probable or possible AD. Caregivers were family members living with the demented individuals in the community. Physical performance was measured using walking speed, functional reach, and standing balance. Health status was measured with the Medical Outcomes Study Short Form, the Sickness Impact Profile, and caregiver reports of subject's restricted activity days, bed disability days, falls, and exercise participation. Baseline data indicated that persons with AD were impaired on measures of physical performance and function, compared to published data on nondemented older adults. During a 12-wk treatment period, caregivers were taught to guide their demented charges in an individualized program of endurance activities (primarily walking), strength training, and balance and flexibility exercises. Adherence data indicated that 100% of the subjects were compliant with some exercise recommendations, and one-third completed all assigned exercises during the training period. Caregivers were able to learn and direct subjects during scheduled exercise activities. These findings indicate that the integration of exercise training into the care of persons with AD is both needed and feasible. Further research is currently underway to determine the efficacy of this approach for reducing additional physical disability in these individuals.