Dependency rather than old age increases the risk of warfarin-related bleeding

There is uncertainty about the safety of anticoagulation with warfarin in the elderly. This cohort study investigated the risk factors for warfarin-related bleeding in a primary care setting. In multiple regression analyses increased risk of bleeding was associated with domiciliary monitoring of int...

Full description

Saved in:
Bibliographic Details
Published inBritish journal of general practice Vol. 54; no. 506; pp. 690 - 692
Main Authors Goudie, Barclay M, Donnan, Peter T, Fairfield, Geraldine, Al-Agilly, Sally S, Cachia, Philip G
Format Journal Article
LanguageEnglish
Published England Oxford University Press 01.09.2004
Subjects
Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Anticoagulants - adverse effects
Brief Reports
Dependency (Psychology)
Female
Hemorrhage - chemically induced
Humans
International Normalized Ratio
Male
Middle Aged
Regression Analysis
Risk Assessment
Risk Factors
Sex Factors
Warfarin - adverse effects
Online AccessGet full text

Cover

More Information
Summary:There is uncertainty about the safety of anticoagulation with warfarin in the elderly. This cohort study investigated the risk factors for warfarin-related bleeding in a primary care setting. In multiple regression analyses increased risk of bleeding was associated with domiciliary monitoring of international normalised ratio (INR), low proportion of INR tests in the target range, high intensity of anticoagulation, and male sex. Age was not associated with increased risk after adjustment. High levels of dependency, not old age, should raise concerns about the safety of anticoagulation with warfarin.
ISSN:0960-1643