Meta-analysis of effects of microbial phytase on digestibility and bioavailability of copper and zinc in growing pigs

A meta-analysis was conducted to determine the effect of microbial phytase in pig diets on digestibility and bioavailability of Cu and Zn. Studies (n = 22) into effects of microbial phytase on digestibility and plasma levels of Cu and Zn were included in a dataset and regression analysis was perform...

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Bibliographic Details
Published inJournal of animal science Vol. 90 Suppl 4; pp. 134 - 136
Main Authors Bikker, P, Jongbloed, A W, Thissen, J T N M
Format Journal Article
LanguageEnglish
Published United States 01.12.2012
Subjects
6-Phytase - metabolism
6-Phytase - pharmacology
Animals
Biological Availability
Copper - blood
Copper - pharmacokinetics
dietary zinc
piglets
Swine - growth & development
Swine - physiology
Zinc - blood
Zinc - pharmacokinetics
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Summary:A meta-analysis was conducted to determine the effect of microbial phytase in pig diets on digestibility and bioavailability of Cu and Zn. Studies (n = 22) into effects of microbial phytase on digestibility and plasma levels of Cu and Zn were included in a dataset and regression analysis was performed to quantify the effect of Aspergillus niger derived 3-phytase in studies (n = 14) with a maximum dietary Zn content of 100 mg/kg and a maximum Cu addition of 20 mg/kg. Phytase inclusion increased digestibility of Zn (P = 0.003) and plasma Zn content (P < 0.001) without affecting digestibility and plasma level of Cu. Based on a comparison with dose-response studies with Zn, we estimated 500 phytase units (FTU) of microbial phytase is equivalent to 27 mg of Zn from ZnSO(4).
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
ObjectType-Review-3
content type line 23
ISSN:0021-8812
1525-3163
DOI:10.2527/jas.53798