The detection by cellular electrophoresis of surface antibodies on human lymphocytes

The electrophoretic mobility of peripheral blood lymphocytes from human subjects with positive Mantoux tests was measured before and after treatment with purified protein derivative. Lymphocytes from subjects with negative Mantoux reactions were used as controls. A large number of the first group ly...

Full description

Saved in:
Bibliographic Details
Published inClinical and experimental immunology Vol. 5; no. 6; pp. 669 - 672
Main Authors Bert, G, Lajolo di Cossano, D, Pecco, P
Format Journal Article
LanguageEnglish
Published England 01.12.1969
Subjects
Antibodies - analysis
Electrophoresis
Humans
In Vitro Techniques
Lymphocytes - immunology
Methods
Techniques
Tuberculin Test
Tuberculosis - immunology
Online AccessGet full text

Cover

More Information
Summary:The electrophoretic mobility of peripheral blood lymphocytes from human subjects with positive Mantoux tests was measured before and after treatment with purified protein derivative. Lymphocytes from subjects with negative Mantoux reactions were used as controls. A large number of the first group lymphocytes showed a reduction of electrophoretic mobility and hence of the surface electrical charge. The mobility of the control cells submitted to the same treatment was unchanged. The possible presence of cytophilic antibodies or of cellular specific receptors on the lymphocyte surface is discussed.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0009-9104
1365-2249