Evaluation of the Integrated Tuberculosis Research Program Sponsored by the Spanish Society of Pulmonology and Thoracic Surgery: 11 Years on

• Published in: Archivos de bronconeumología (English ed.) Vol. 56; no. 8; pp. 483 - 492
• Main Authors: Rodrigo, Teresa, García-García, José-María, Caminero, José A, Ruiz-Manzano, Juan, Anibarro, Luis, García-Clemente, Marta M, Gullón, José A, Jiménez-Fuentes, M Ángeles, Medina, Juan F, Mir, Isabel, Penas, Antón, Sánchez, Francisca, Souza-Galvão, Maria Luiza De, Caylà, Joan A
• Format: Journal Article
• Language: English; Spanish
• Published: 01.08.2020
• ISSN: 1579-2129
• DOI: 10.1016/j.arbres.2019.10.006

OBJECTIVEThe objective of the study was to determine the trend of variables related to tuberculosis (TB) from the Integrated Tuberculosis Research Program (PII-TB) registry of the Spanish Society of Pulmonology and Thoracic Surgery (SEPAR), and to evaluate the PII-TB according to indicators related to its scientific objectives. METHODCross-sectional, population-based, multicenter study of new TB cases prospectively registered in the PII-TB between 2006 and 2016. The time trend of quantitative variables was calculated using a lineal regression model, and qualitative variables using the χy test for lineal trend. RESULTSA total of 6,892 cases with an annual median of 531 were analyzed. Overall, a significant downward trend was observed in women, immigrants, prisoners, and patients initially treated with 3 drugs. Significant upward trends were observed in patients aged 40-50 and > 50 years, first visit conducted by a specialist, hospitalization, diagnostic delay, disseminated disease and single extrapulmonary location, culture(+), sensitivity testing performed, drug resistance, directly observed treatment, prolonged treatment, and death from another cause. The scientific objectives of the PII-TB that showed a significant upward trend were publications, which reached a maximum of 8 in 2016 with a total impact factor of 49,664, numbers of projects initiated annually, presentations at conferences, and theses. CONCLUSIONSPII-TB provides relevant information on TB and its associated factors in Spain. A large team of researchers has been created; some scientific aspects of the registry were positive, while others could have been improved.