Emerging Topics in Cancer Evolution

Cancer results from an evolutionary process that yields a heterogeneous tumor with distinct subpopulations and varying sets of somatic mutations. This perspective discusses computational methods to infer models of evolutionary processes in cancer that aim to improve our understanding of tumorigenesi...

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Bibliographic Details
Published inPacific Symposium on Biocomputing. Pacific Symposium on Biocomputing Vol. 27; p. 397
Main Authors El-Kebir, Mohammed, Morris, Quaid, Oesper, Layla, Sahinalp, S Cenk
Format Journal Article
LanguageEnglish
Published United States 2022
Subjects
Computational Biology
Humans
Mutation
Neoplasms - genetics
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Summary:Cancer results from an evolutionary process that yields a heterogeneous tumor with distinct subpopulations and varying sets of somatic mutations. This perspective discusses computational methods to infer models of evolutionary processes in cancer that aim to improve our understanding of tumorigenesis and ultimately enhance current clinical practice.
ISSN:2335-6936
DOI:10.1142/9789811250477_0036