Fmoc Solid-Phase Peptide Synthesis

Synthetic peptides are important as drugs and in research. Currently, the method of choice for producing these compounds is solid-phase peptide synthesis. In this nonspecialist review, we describe the scope and limitations of Fmoc solid-phase peptide synthesis. Furthermore, we provide a detailed pro...

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Bibliographic Details
Published inMethods in molecular biology (Clifton, N.J.) Vol. 1348; p. 33
Main Authors Hansen, Paul R, Oddo, Alberto
Format Journal Article
LanguageEnglish
Published United States 2015
Subjects
Amino Acids - chemistry
Fluorenes - chemistry
Peptides - chemical synthesis
Peptides - chemistry
Solid-Phase Synthesis Techniques
Fmoc solid-phase synthesis
Linkers
Resins
Coupling reagents
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Summary:Synthetic peptides are important as drugs and in research. Currently, the method of choice for producing these compounds is solid-phase peptide synthesis. In this nonspecialist review, we describe the scope and limitations of Fmoc solid-phase peptide synthesis. Furthermore, we provide a detailed protocol for Fmoc peptide synthesis.
ISSN:1940-6029
DOI:10.1007/978-1-4939-2999-3_5