Amniotic fluid adenosine 3',5' - monophosphate in prostaglandin-induced midtrimester abortions

• Published in: Obstetrics and gynecology (New York. 1953) Vol. 49; no. 2; p. 223
• Main Authors: Weiss, P R, Sulimovici, S, Macri, J N, Robins, J, Roginsky, M S
• Format: Journal Article
• Language: English
• Published: United States 01.02.1977
• Subjects: Abortion, Induced; Adult; Amniotic Fluid - metabolism; Cyclic AMP - metabolism; Female; Fetal Distress - diagnosis; Fetal Distress - metabolism; Humans; Pregnancy; Pregnancy Trimester, Second; Prostaglandins F - administration & dosage; Prostaglandins F - therapeutic use

Cyclic adenosine 3'5-monophosphate (cAMP) was serially measured in the amniotic fluid (AF) of 9 patients undergoing midtrimester abortions induced by intraamniotic prostaglandins. The results demonstrate an increase in AF cAMP ranging from 2- to 7-fold within the 6 hours of observation. The fet...