Target-triggered, self-powered DNAzyme–MnO2 nanosystem: towards imaging microRNAs in living cells

A target-triggered, self-powered strategy for in situ monitoring of intracellular microRNAs was fabricated via a versatile DNAzyme–MnO2 nanosystem, which integrates delivery, quenching, target recognition, self-supply of cofactors and signal amplification all in one.

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Published inChemical communications (Cambridge, England) Vol. 55; no. 89; pp. 13366 - 13369
Main Authors Cui, Mei-Rong, Li, Xiang-Ling, Xu, Jing-Juan, Chen, Hong-Yuan
Format Journal Article
LanguageEnglish
Published Cambridge Royal Society of Chemistry 05.11.2019
Subjects
chemical compounds
chemical reactions
image analysis
Manganese dioxide
microRNA
MicroRNAs
monitoring
nanotechnology
Target recognition
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Abstract A target-triggered, self-powered strategy for in situ monitoring of intracellular microRNAs was fabricated via a versatile DNAzyme–MnO2 nanosystem, which integrates delivery, quenching, target recognition, self-supply of cofactors and signal amplification all in one.
AbstractList A target-triggered, self-powered strategy for in situ monitoring of intracellular microRNAs was fabricated via a versatile DNAzyme–MnO2 nanosystem, which integrates delivery, quenching, target recognition, self-supply of cofactors and signal amplification all in one.
A target-triggered, self-powered strategy for in situ monitoring of intracellular microRNAs was fabricated via a versatile DNAzyme–MnO₂ nanosystem, which integrates delivery, quenching, target recognition, self-supply of cofactors and signal amplification all in one.
A target-triggered, self-powered strategy for in situ monitoring of intracellular microRNAs was fabricated via a versatile DNAzyme-MnO2 nanosystem, which integrates delivery, quenching, target recognition, self-supply of cofactors and signal amplification all in one.A target-triggered, self-powered strategy for in situ monitoring of intracellular microRNAs was fabricated via a versatile DNAzyme-MnO2 nanosystem, which integrates delivery, quenching, target recognition, self-supply of cofactors and signal amplification all in one.
Author Chen, Hong-Yuan
Xu, Jing-Juan
Cui, Mei-Rong
Li, Xiang-Ling
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Snippet A target-triggered, self-powered strategy for in situ monitoring of intracellular microRNAs was fabricated via a versatile DNAzyme–MnO2 nanosystem, which...
A target-triggered, self-powered strategy for in situ monitoring of intracellular microRNAs was fabricated via a versatile DNAzyme-MnO2 nanosystem, which...
A target-triggered, self-powered strategy for in situ monitoring of intracellular microRNAs was fabricated via a versatile DNAzyme–MnO₂ nanosystem, which...
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SubjectTerms chemical compounds
chemical reactions
image analysis
Manganese dioxide
microRNA
MicroRNAs
monitoring
nanotechnology
Target recognition
Title Target-triggered, self-powered DNAzyme–MnO2 nanosystem: towards imaging microRNAs in living cells
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