Transformers

The accepted wisdom, that the use of engineered cells to treat diseases must involve stem cells, has been challenged by Philippe Collas of Oslo University, who believes he has found another way to create cells for transplants and therapy that are compatible with the patient's tissue type and im...

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Bibliographic Details
Published inNew scientist (1971) Vol. 176; no. 2364; pp. 38 - 41
Main Author Westphal, S P
Format Magazine Article
LanguageEnglish
Published London New Scientist 12.10.2002
Subjects
Biology
Cell biology
Cells
Collas, Philippe
Diabetes
Embryos
Fetuses
Fibroblasts
Gene expression
Gene therapy
Genetic engineering
Immune system
Lymphocytes
Researchers
Skin
Stem cells
Tissue engineering
Transplants
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Summary:The accepted wisdom, that the use of engineered cells to treat diseases must involve stem cells, has been challenged by Philippe Collas of Oslo University, who believes he has found another way to create cells for transplants and therapy that are compatible with the patient's tissue type and immune system. His method involves a skin biopsy followed by a technique for teaching the cells to become the type of cell that patient requires. This claim challenges one of biology's most established dogmas; that once an adult cell has developed into its specialized cell type, it is not possible to force it to switch to become a different type. (Quotes from original text)
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ISSN:0262-4079
2059-5387