Neuromodulation for eating disorders: obesity and anorexia

Extremes of eating disorders (ED) have become prevalent in both developed and developing countries. Available therapies, though largely effective, fail in a substantial number of patients and carry considerable side effects. Morbid obesity and anorexia nervosa (AN) represent important causes of morb...

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Published inNeurosurgery clinics of North America Vol. 25; no. 1; p. 147
Main Authors Gorgulho, Alessandra A, Pereira, Julio L B, Krahl, Scott, Lemaire, Jean-Jacques, De Salles, Antonio
Format Journal Article
LanguageEnglish
Published United States 01.01.2014
Subjects
Anorexia - therapy
Deep Brain Stimulation
Humans
Hypothalamus - physiology
Obesity - therapy
Hypothalamus
Deep brain stimulation
Neuromodulation
Eating disorders
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Summary:Extremes of eating disorders (ED) have become prevalent in both developed and developing countries. Available therapies, though largely effective, fail in a substantial number of patients and carry considerable side effects. Morbid obesity and anorexia nervosa (AN) represent important causes of morbidity and mortality among young adults. Morbid obesity affects disproportionate numbers of children. AN is also important for its high mortality in young adults. The challenges of effectively treating AN are well recognized. In this article, important aspects of ED are reviewed in detail and novel approaches to the treatment of ED are proposed.
ISSN:1558-1349
DOI:10.1016/j.nec.2013.08.005