Clinical Test for Validation of a New Optical Probe for Hemodynamic Parameters Assessment

• Published in: Biomedical Engineering Systems and Technologies Vol. 452; pp. 269 - 283
• Main Authors: Pereira, T., Santos, I., Oliveira, T., Vaz, P., Santos Pereira, T., Santos, H., Almeida, V., Pereira, H. C., Correia, C., Cardoso, J.
• Format: Book Chapter
• Language: English
• Published: Germany Springer Berlin / Heidelberg 2014; Springer Berlin Heidelberg
• Series: Communications in Computer and Information Science
• Subjects: Biomedical engineering; Health & safety aspects of computing; Hemodynamic parameters; Life sciences: general issues; Optical probe; Pulse wave velocity; Pulse waveform analysis; Waveform distension
• ISBN: 9783662444849; 3662444844
• ISSN: 1865-0929; 1865-0937
• DOI: 10.1007/978-3-662-44485-6_19

The assessment of the cardiovascular system condition based on multiple parameters allows a more precise and accurate diagnosis of the heart and arterial tree condition. For this reason, the interest in non-invasive devices has presently increased in importance. In this work, an optical probe was tested in order to validate this technology for measuring multiple parameters such as Pulse Wave Velocity (PWV) or Augmentation Index (AIx), amongst others. The PWV measured by the optical probe was previously compared with the values obtained with the gold-standard system. Another analysis was performed in 131 young subjects to establish carotid PWV reference values as well as other hemodynamic parameters and to find correlations between these and the population characteristics. The results allowed us to conclude that this new technique is a reliable method to determine these parameters. The range of the obtained values for local PWV are in agreement with the values obtained by other studies, and significant correlations with age and smoking status were found. The AIx varied between −6.15 % and 11.46 % and exhibit a negative correlation with heart rate, and dP/dtmax shows a significant decrease with age.