Comparison of pirenzepine with cimetidine in duodenal ulcer disease - a short-term maintenance study

Sixty-seven patients with endoscopically proven duodenal ulceration were entered into a double-blind study and randomized to treatment with pirenzepine (PZ) (Gastrozepin; Boehringer Ingelheim) 50 mg twice daily or cimetidine (CM) (Tagamet Smith Kline & French Laboratories) 400 mg twice daily, gi...

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Bibliographic Details
Published inSouth African medical journal Vol. 70; no. 1; pp. 27 - 30
Main Author Marks, I.N., Wright, J.P., Bank, L., Girdwood, A.H., Kalvaria, I., Gilinsky, N.H., O'Keefe, S.J.O. & Lucke, W.
Format Journal Article
LanguageEnglish
Published South Africa Health and Medical Publishing Group (HMPG) 05.07.1986
Subjects
Adult
Antacids - administration & dosage
Anti-Ulcer Agents - therapeutic use
Benzodiazepinones - adverse effects
Benzodiazepinones - therapeutic use
Cimetidine
Cimetidine - adverse effects
Cimetidine - therapeutic use
Clinical Trials as Topic
Double-Blind Method
Duodenal Ulcer - drug therapy
Duodenal ulcer disease
Duodenal ulcer healing
Female
Gastroenterology
Humans
Male
Middle Aged
Pharmacology
Pirenzepine
Random Allocation
Side-effects
Time Factors
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Summary:Sixty-seven patients with endoscopically proven duodenal ulceration were entered into a double-blind study and randomized to treatment with pirenzepine (PZ) (Gastrozepin; Boehringer Ingelheim) 50 mg twice daily or cimetidine (CM) (Tagamet Smith Kline & French Laboratories) 400 mg twice daily, given 30 minutes before breakfast and supper.
ISSN:0256-9574
2078-5135