Uterine contractions: an unusual side effect of venom immunotherapy

Venom immunotherapy (VIT) is an efficient treatment modality for preventing further sting-induced anaphylactic reactions in patients with Hymenoptera venom allergy. The main side effects of VIT include local and systemic allergic reactions with a variable risk of up to 46%. We report the case of a w...

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Bibliographic Details
Published inJournal of investigational allergology & clinical immunology Vol. 20; no. 5; pp. 431 - 432
Main Authors Karakurt, F, Kargili, A, Bozkurt, B, Kasapoglu, B, Ikizek, M
Format Journal Article
LanguageEnglish
Published Spain 2010
Subjects
Animals
Apis mellifera
Bee Venoms - adverse effects
Bee Venoms - therapeutic use
Bees - immunology
Bites and Stings - diagnosis
Bites and Stings - immunology
Bites and Stings - physiopathology
Bites and Stings - therapy
Bronchial Spasm
Calcium - administration & dosage
Desensitization, Immunologic - adverse effects
Female
Humans
Hymenoptera
Hypersensitivity - diagnosis
Hypersensitivity - immunology
Hypersensitivity - physiopathology
Hypersensitivity - therapy
Hypocalcemia - etiology
Hypocalcemia - prevention & control
Middle Aged
Patient Selection
Urticaria
Uterine Contraction - drug effects
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Summary:Venom immunotherapy (VIT) is an efficient treatment modality for preventing further sting-induced anaphylactic reactions in patients with Hymenoptera venom allergy. The main side effects of VIT include local and systemic allergic reactions with a variable risk of up to 46%. We report the case of a woman who experienced rapid-onset hypocalcemia and regular uterine contractions on 3 occasions within 30 minutes of receiving Apis mellifera VIT. To the best of our knowledge, this is the first report of uterine contractions as a side effect of VIT. The importance of this event is clear, as VIT has now been approved for pregnant women. We provide recommendations to physicians using this modality.
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ISSN:1018-9068