Polyomavirus-associated nephropathy: critical issues in virological monitoring

Polyomavirus-associated nephropathy is one of the most common viral complications in renal transplant recipients. Viral replication is the single common feature of all patients at risk of nephropathy. Therefore, screening for virus replication allows for the identification of patients at risk of dev...

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Bibliographic Details
Published inThe New microbiologica Vol. 32; no. 3; pp. 235 - 243
Main Authors Cavallo, Rossana, Bergallo, Massimiliano, Sidoti, Francesca, Astegiano, Sara, Terlizzi, Maria Elena, Costa, Cristina
Format Journal Article
LanguageEnglish
Published Italy 01.07.2009
Subjects
Humans
Immunosuppression
Kidney Diseases - complications
Kidney Diseases - prevention & control
Kidney Transplantation
Mass Screening
Polyomavirus - physiology
Polyomavirus Infections - complications
Polyomavirus Infections - prevention & control
Polyomavirus Infections - virology
Postoperative Complications
Risk Factors
Virus Replication
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Summary:Polyomavirus-associated nephropathy is one of the most common viral complications in renal transplant recipients. Viral replication is the single common feature of all patients at risk of nephropathy. Therefore, screening for virus replication allows for the identification of patients at risk of developing nephropathy and permits earlier intervention, in particular a pre-emptive reduction of immunosuppression, with improvement of outcome. This paper describes the modes of virological monitoring and its role in the clinical management of renal transplant patients.
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ISSN:1121-7138